Effects of the Oral Prostaglandin F2 Alpha Receptor Antagonist Tocolytic OBE022 on Reproduction in Rats and Rabbits

March 10, 2018

OBE022

Oliver Pohl, Roberta Sisti, Jean-Pierre Gotteland SRI Conference, 06-10 March 2018, San Diego, CA

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Safety and Pharmacokinetics of the Oral Prostaglandin F2 Alpha Receptor Antagonist Tocolytic OBE022: A First-in-Human Study in Healthy Women

OBE022

Oliver Pohl, Ulrike Lorch, Line Marchand, Jean-Pierre Gotteland SRI Conference, 06-10 March 2018, San Diego, CA

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Confirmation of the Cardiac Safety of PGF2α Receptor Antagonist OBE022 in a First-in-Human Study in Healthy Subjects, Using Intensive ECG Assessments

February 28, 2018

OBE022

Jörg Täubel, Ulrike Lorch, Simon Coates, Sara Fernandes, Paul Foley, Georg Ferber, Jean-Pierre Gotteland, Oliver Pohl Confirmation of the Cardiac…

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GnRH Receptor Antagonist Mono- And Combination Therapy With E2/NETA Add-Back – Pharmacodynamics And Safety Of OBE2109

December 4, 2017

Linzagolix

GnRH Receptor Antagonist Mono- And Combination Therapy With E2/NETA Add-Back – Pharmacodynamics And Safety Of OBE2109S Pohl O, Marchand L,…

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Confirmation of the Cardiac Safety of OBE022 in a First in Human Study in Healthy Subjects using Intensive ECG Assessments and the Effect of a Meal on QTc to Show Assay Sensitivity

September 19, 2017

OBE022

J. Täubel, U. Lorch , G. Ferber , O Pohl ACCP Conference, 17-19 September 2017, San Diego, CA

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A placebo-controlled, randomized, double-blind study of pregnancy and live birth rates after single oral administration of a novel oxytocin antagonist, nolasiban, prior to embryo transfer

July 5, 2017

Nolasiban

H. Tournaye, A. Humberstone, V. Lecomte, P. Terrill, P. Pierzynski, E. Loumaye ESHRE 33rd Annual Meeting, 2-5 July 2017, Geneva,…

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Combination tocolytics on the inhibition of OT-induced contractions of human pregnant myometrium in vitro

Nolasiban

L. Riaposova, S.H. Kim, O. Pohl, A. Chollet, J.P. Gotteland, A. Hanyaloglu, P. Bennett, V. Terzidou ESHRE 33rd Annual Meeting,…

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FP receptor antagonist, OBE002, inhibits both PGF2α- and OT-induced contractions of human pregnant myometrium in vitro

Nolasiban

L. Riaposova, S.H. Kim, O. Pohl, A. Chollet, J.P. Gotteland, A. Hanyaloglu, P. Bennett, V. Terzidou ESHRE 33rd Annual Meeting,…

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Differential Effects of Oxytocin Receptor Antagonists, Atosiban and Nolasiban, on Oxytocin Receptor–Mediated Signaling in Human Amnion and Myometrium

April 1, 2017

Nolasiban

Differential Effects of Oxytocin Receptor Antagonists, Atosiban and Nolasiban, on Oxytocin Receptor–Mediated Signaling in Human Amnion and Myometrium Sung Hye…

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THE ‘ART’ OF WOMEN’S HEALTH – Add back or not add back? Obseva: Both options good as UF, endo trials continue

March 30, 2017

Linzagolix

THE ‘ART’ OF WOMEN’S HEALTH – Add back or not add back? Obseva: Both options good as UF, endo trials…

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