The Effect of Linzagolix on Bone Mineral Density (BMD): Safety Results From a Dose-Ranging Trial

May 20, 2019

Linzagolix

Elke Bestel, Andrew Humberstone, Veronique Lecomte, Ernest Loumaye, Jean-Pierre Gotteland, James A. Simon ACOG Annual Conference, 03-06 May 2019, Nashville,…

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Oxytocin Receptor Antagonists, Atosiban and Nolasiban, Inhibit Prostaglandin F2α-induced Contractions and Inflammatory Responses in Human Myometrium

April 8, 2019

Nolasiban

Sung Hye Kim, Lucia Riaposova, Hauwa Ahmed, Oliver Pohl, André Chollet, Jean-Pierre Gotteland, Aylin Hanyaloglu, Phillip R. Bennett & Vasso…

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Co‐administration of the prostaglandin F2α receptor antagonist pre‐term labour drug candidate OBE022 with magnesium sulfate, atosiban, nifedipine and betamethasone

March 25, 2019

OBE022

Co‐administration of the prostaglandin F2α receptor antagonist pre‐term labour drug candidate OBE022 with magnesium sulfate, atosiban, nifedipine and betamethasone Oliver…

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Safety and Pharmacokinetics of the Oral Prostaglandin F2alpha Receptor Antagonist, OBE022, in Patients With Threatened Spontaneous Preterm Labor

March 18, 2019

OBE022

Andrew Humberstone, Jose Luis Bartha, Seppo Heinonen, Juha Räsänen, Aydin Tekay, Michel Brethous, Jean-Pierre Gotteland, Oliver Pohl, Ernest Loumaye SRI…

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Efficient Design of Integrated and Adaptively Interlinked Protocols for Early-Phase Drug Development Programs

January 28, 2019

OBE022

Efficient Design of Integrated and Adaptively Interlinked Protocols for Early-Phase Drug Development Programs Simon Coates, Oliver Pohl, Jean-Pierre Gotteland, Jörg…

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A Placebo-Controlled, Randomized, Double-Blind, Phase 3 Study Assessing Ongoing Pregnancy Rates After Single Oral Administration of a Novel Oxytocin Receptor Antagonist, Nolasiban, Prior to Single Embryo Transfer

October 9, 2018

Nolasiban

Visnova H., Tournaye H. J., Humberstone A., Terrill P., Macgregor L., Loumaye E. ASRM 2018, 6-10 October 2018, Denver, CO

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Effects of the oral oxytocin receptor antagonist nolasiban on early embryonic development

July 4, 2018

Nolasiban

O. Pohl, D. Perks, R. Sisti, J.P. GottelandESHRE Annual Conference, 01-04 July 2018, Barcelona, Spain

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OBE022, an oral and selective prostaglandin F2α receptor antagonist as an effective and safe modality for the treatment of preterm labor

May 18, 2018

OBE022

OBE022, an oral and selective prostaglandin F2α receptor antagonist as an effective and safe modality for the treatment of preterm…

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Pharmacokinetics, safety and tolerability of OBE022, a selective prostaglandin F2α receptor antagonist tocolytic: A first-in-human trial in healthy postmenopausal women

April 30, 2018

OBE022

Pharmacokinetics, safety and tolerability of OBE022, a selective prostaglandin F2α receptor antagonist tocolytic: A first-in-human trial in healthy postmenopausal women…

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ObsEva on page 17 of Understanding Fertility Special Report 2018

April 24, 2018

Nolasiban

Special report in the Raconteur Article in ‘The Times’ Click here for publication link IVF ‘BREAKTHROUGH’ TREATMENT Pioneering use of…

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