Reproductive Health & Pregnancy Therapeutics

Uterine Fibroids (UF)

Uterine fibroids are common non-cancerous tumors that grow within the muscular wall of the uterus. They can vary in size and number and when symptomatic, are most often accompanied by heavy menstrual bleeding (HMB), anemia, abdominal pressure and pain, bloating, increased urinary frequency and reproductive dysfunction. Uterine fibroids are associated with an increased risk of pregnancy complications such as infertility, miscarriage, placental abruption, and early onset of labor.

For the millions of women with symptomatic uterine fibroids seeking treatment options, selection is driven by symptom severity, the woman’s age, and her desire to have children now or in the future. While medical, surgical and minimally invasive treatments are available, the standard of care for symptomatic uterine fibroids is a hysterectomy or, in women who wish to preserve their fertility, surgical removal of the fibroid(s).

An Advancement in the Treatment of Uterine Fibroids

ObsEva is currently advancing Linzagolix, a novel, oral gonadotropin-releasing hormone (GnRH) receptor antagonist that potentially provides effective management of UF-associated HMB while mitigating bone mineral density loss and other adverse effects typically associated with currently approved treatments.

Click here for further information on the development of Linzagolix for the treatment of uterine fibroids

Click here to view clinical trial details

Click here if you have uterine fibroids and are interested to participate in a trial