GnRH Receptor Antagonist Mono- And Combination Therapy With E2/NETA Add-Back – Pharmacodynamics And Safety Of OBE2109
December 4, 2017
Linzagolix
Pohl O, Marchand L, Fawkes N, Gotteland JP, Loumaye E.
Read moreConfirmation of the Cardiac Safety of OBE022 in a First in Human Study in Healthy Subjects using Intensive ECG Assessments and the Effect of a Meal on QTc to Show Assay Sensitivity
September 19, 2017
OBE022
J. Täubel, U. Lorch , G. Ferber , O Pohl
ACCP Conference, 17-19 September 2017, San Diego, CA
Poster 019: Page 16
A placebo-controlled, randomized, double-blind study of pregnancy and live birth rates after single oral administration of a novel oxytocin antagonist, nolasiban, prior to embryo transfer
July 5, 2017
Nolasiban
H. Tournaye, A. Humberstone, V. Lecomte, P. Terrill, P. Pierzynski, E. Loumaye
ESHRE 33rd Annual Meeting, 2-5 July 2017, Geneva, Switzerland
Abstract O-024: Page i12
Combination tocolytics on the inhibition of OT-induced contractions of human pregnant myometrium in vitro
Nolasiban
L. Riaposova, S.H. Kim, O. Pohl, A. Chollet, J.P. Gotteland, A. Hanyaloglu, P. Bennett, V. Terzidou
ESHRE 33rd Annual Meeting, 2-5 July 2017, Geneva, Switzerland
Abstract O-119: Page i54
FP receptor antagonist, OBE002, inhibits both PGF2α- and OT-induced contractions of human pregnant myometrium in vitro
OBE022
L. Riaposova, S.H. Kim, O. Pohl, A. Chollet, J.P. Gotteland, A. Hanyaloglu, P. Bennett, V. Terzidou
ESHRE 33rd Annual Meeting, 2-5 July 2017, Geneva, Switzerland
Abstract P-692: Page i452
Differential Effects of Oxytocin Receptor Antagonists, Atosiban and Nolasiban, on Oxytocin Receptor–Mediated Signaling in Human Amnion and Myometrium
April 1, 2017
Nolasiban
Sung Hye Kim, Oliver Pohl, Andre Chollet, Jean-Pierre Gotteland, Adam D. J. Fairhurst, Phillip R. Bennett, and Vasso Terzidou
Read moreTHE ‘ART’ OF WOMEN’S HEALTH – Add back or not add back? Obseva: Both options good as UF, endo trials continue
March 30, 2017
Linzagolix
THE ‘ART’ OF WOMEN’S HEALTH – Add back or not add back? Obseva: Both options good as UF, endo trials…
Read moreBoth OTR Antagonists, Atosiban and Nolasiban, Inhibits PGE2/PGF2α-Induced Contractions of Human Pregnant Myometrium In Vitro
March 18, 2017
Nolasiban
Sung Hye Kim, Hauwa Ahmed, Lucia Riaposova, Oliver Pohl, Andre Chollet, Aylin Hanyaloglu, Phillip R Bennett, Vasso Terzidou
SRI Conference, 15-18 March 2017, Orlando, FL
Abstract S-031: Page 245A
Scientific Abstracts Reproductive Sciences Vol. 24 (1_suppl), 1A-51A, March 2017
Read moreThe OTR Antagonist, OBE001, Inhibits Both Spontaneous and OT-Induced Contractions of Human Pregnant Myometrium In Vitro
March 16, 2016
Nolasiban
Shankari Arulkumaran, Sung Hye Kim, Oliver Pohl, Andre Chollet, Phillip R. Bennett and Vasso Terzidou
SRI Conference, 16-19 March 2016, Montreal, Canada
Abstract S-096
Scientific Abstracts. (2016). Reproductive Sciences, 23(1_suppl), 51A-344A
Read moreThe OTR Antagonist, OBE001, Inhibits OT-Driven Proinflammatory Effects in Both Human Myometrium and Amnion
Nolasiban
Sung Hye Kim, Oliver Pohl, Andre Chollet, Adam Fairhurst, Phillip R Bennett, Vasso Terzidou
SRI Conference, 16-19 March 2016, Montreal, Canada
Abstract T-071: Page 123A
Scientific Abstracts. (2016). Reproductive Sciences, 23(1_suppl), 51A-344A
Read more